Common use

Methylcobalamin is one of vitamin B12 forms and used to treat diseases of the peripheral nervous system such as neuralgia, polyneuropathy, radiculopathy and also chronic hepatitis, fatty degeneration of the liver, liver cirrhosis, chronic pancreatitis. The medication improves exercise performance and is also used in sport.

Vitamin B12 participates in processes of transmethylation, in synthesis of proteins and nucleic acids, carbohydrate and lipids, stimulates monooxygenase system, has a protective effect on SH-groups of glutathione and activates the liver. Has anabolic effect (increasing physical performance), regenerating effect on mechanical and toxic damage of the nerve trunks. In diseases of the peripheral nervous system, reduces pain, promotes recovery of motor function and reduce autonomic disorders. Providing hepatoprotective effect, a favorable effect on liver function in toxic hepatitis, liver cirrhosis, pancreatitis. Reduces the damage of the joints with adjuvant arthritis, has hematopoietic effect.



Dosage and direction

The medication is taken orally. To treat the peripheral nervous system a recommended dose of Methylcobalamin is 10 mg taken once daily. The complex treatment of liver disease and pancreatitis requires 5 mg of Methylcobalamin taken 2 times a day or 10 mg taken 1 time a day. Treatment should be done during 3-4 weeks. Put tablet under the tongue and so it could be dissolved slowly, change its place to save your mucous membrane from irritation.



Precautions

If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.



Contraindications

In person with hypersensitivity to Methylcobalamin.



Possible side effect

Allergic reactions are most common side effects, they symptoms are: swelling of face and tongue, rash.



Drug interaction

Inform your health care advisor about any prescribed medications and herbal products and especially about: Anticonvulsants, Aspirin, AZT, Cimetidine, Clofibrate, Colchicine, Cycloserine, Erythromycin, Famotidine, Fenofibrate, Gabapentin, Gentamicin, Isoniazid, Lansoprazole, Metformin, Methyldopa, Neomycin, Nitrous Oxide, Nizatidine, Omeprazole, oral contraceptives, Phenobarbital, Ranitidine, Sulfamethoxazole, Tetracycline, Tricyclic, antidepressants, Trimethoprim, valproic acid. There are rathermany drugs able to reduce the absorption of vitamin B12. Proton pump inhibitors (e.g., omeprazole and lansoprazole) significantly reduce stomach acid secretion required for the release of vitamin B12 from food but not from supplements. Prolonged use of proton pump inhibitors has been found to decrease blood vitamin B12 levels. Gastric acid inhibitors such as H2-receptor antagonists (e.g., Tagamet, Pepsid, Zantac) also decrease the absorption of vitamin B12 from food. Cholestyramine, chloramphenicol, neomycin colchicine are also able to inhibit vitamin B12 absorption from food. Metformin (a medication for individuals with type 2 diabetes) decreases vitamin B12 absorption.



Missed dose

Take the missed dose as soon as possible unless it is almost time of your next dose just skip the missed dose and return to your regular schedule.



Overdose

The symptoms of a vitaminMethylcobalamin overdose are a numbing and tingling in the extremities. Stop taking vitamin Methylcobalamin if you experience these symptoms. Megadoses of vitamin B12 may cause leukemia, prostate cancer. Diets high in cholesterol, animal protein and vitamin B12 may be associated with certain kinds of stomach and esophagus cancers.



Storage

Store at room temperature in a tight container at the place out of reach of children and pets away from sunlight and moisture.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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